:root{
  --accent:#0b6fbf;
  --accent-dark:#123a64;
  --accent-soft:#edf5ff;
  --success-bg:#d1fae5;
  --success-border:#6ee7b7;
  --success-text:#065f46;
  --danger-bg:#fee2e2;
  --danger-border:#fca5a5;
  --danger-text:#dc2626;
  --muted:#6b7280;
  --bg:#f3f7fb;
  --card:#ffffff;
  --line:#d7e2ee;
  --line-soft:#e9f0f7;
  --text:#15233b;
}

*,
*::before,
*::after{box-sizing:border-box}

html{font-size:16px}

body{
  margin:0;
  color:var(--text);
  font-family:"Segoe UI",Arial,sans-serif;
  background:
    radial-gradient(circle at top left, rgba(14,116,144,0.07), transparent 28%),
    linear-gradient(180deg, #f7fbff 0%, var(--bg) 100%);
}

a{color:inherit}

.topbar .brand{font-weight:700;font-size:18px;color:#2c4066;display:flex;align-items:center;gap:10px;white-space:nowrap}
.topbar-logo{height:40px;width:auto;object-fit:contain;flex-shrink:0;display:block}
.topbar .subtitle{font-size:13px;color:#6b7394;flex:1;min-width:0}
.topbar{
  background:#fff;
  color:#1e2640;
  padding:0 28px;
  height:56px;
  display:flex;
  align-items:center;
  gap:12px;
  border-bottom:1px solid #d4d8e1;
  box-shadow:0 1px 3px rgba(0,0,0,.06);
}

.container{max-width:1600px;margin:26px auto;padding:0 28px}

.search-panel{
  position:relative;
  background:var(--card);
  padding:26px;
  border:1px solid rgba(197,213,228,0.72);
  border-radius:24px;
  box-shadow:0 22px 48px rgba(15,23,42,0.08);
  overflow:visible;
}

.search-panel::before{
  content:"";
  position:absolute;
  inset:0 0 auto 0;
  height:88px;
  background:linear-gradient(90deg, rgba(10,94,168,0.08), rgba(16,185,129,0.05));
  pointer-events:none;
}

.search-controls{
  position:relative;
  display:grid;
  grid-template-columns:minmax(0,1.9fr) auto auto;
  align-items:center;
  gap:14px;
}

.search-input-wrap{
  position:relative;
  display:flex;
  align-items:center;
  min-width:0;
}

.search-controls input{
  width:100%;
  min-height:64px;
  padding:18px 146px 18px 20px;
  border:1px solid #cfdcf3;
  border-radius:18px;
  background:rgba(255,255,255,0.96);
  font-size:18px;
  line-height:1.3;
  box-shadow:inset 0 1px 0 rgba(255,255,255,0.85), 0 8px 20px rgba(15,23,42,0.04);
  transition:border-color .2s, box-shadow .2s;
}

.search-controls input::placeholder{color:#8a96a8}
.search-controls input:focus{
  outline:none;
  border-color:#6d7cff;
  box-shadow:0 0 0 4px rgba(109,124,255,0.12), 0 14px 30px rgba(76,92,161,0.10);
}

.type-hint{
  position:absolute;
  right:12px;
  top:50%;
  transform:translateY(-50%);
  font-size:13px;
  padding:7px 12px;
  border-radius:999px;
  font-weight:700;
  pointer-events:none;
  white-space:nowrap;
}
.type-hint-smiles{background:#d1fae5;color:#065f46;border:1px solid #6ee7b7}
.type-hint-inchi{background:#ede9fe;color:#5b21b6;border:1px solid #c4b5fd}
.type-hint-name{background:#e0f2fe;color:#0369a1;border:1px solid #7dd3fc}

.search-controls button{
  border:none;
  color:#fff;
  cursor:pointer;
  transition:transform .15s, box-shadow .15s, opacity .15s;
}

#fullProfileBtn,
#searchBtn{
  min-height:64px;
  padding:0 24px;
  border-radius:18px;
  font-size:14px;
  font-weight:700;
  letter-spacing:.01em;
  display:flex;
  align-items:center;
  justify-content:center;
  gap:8px;
  box-shadow:0 14px 26px rgba(11,111,191,0.16);
  white-space:nowrap;
}

#fullProfileBtn{background:linear-gradient(135deg,var(--accent-dark) 0%, var(--accent) 100%)}
#searchBtn{background:linear-gradient(135deg,#0f6bb4 0%, #1580d3 100%)}

#fullProfileBtn:hover,
#searchBtn:hover{
  transform:translateY(-1px);
  box-shadow:0 18px 30px rgba(11,111,191,0.20);
}

.options{
  position:relative;
  margin-top:18px;
  display:flex;
  align-items:center;
  gap:10px;
  flex-wrap:wrap;
  color:var(--muted);
}

.results-panel{margin-top:28px}

.card{
  background:var(--card);
  padding:0;
  border:1px solid rgba(204,216,230,0.92);
  border-radius:20px;
  margin-bottom:12px;
  box-shadow:0 10px 26px rgba(15,23,42,0.05);
  overflow:hidden;
}

.card-header{
  display:flex;
  justify-content:space-between;
  align-items:center;
  gap:12px;
  min-height:78px;
  padding:18px 22px;
  background:linear-gradient(180deg, rgba(255,255,255,0.98), rgba(248,251,255,0.94));
  transition:background .15s;
}

.card:not(.collapsed) .card-header{
  border-radius:20px 20px 0 0;
  border-bottom:1px solid #eef2f7;
}

.card-header:hover{background:#f8faff}
.card-header-main{display:flex;align-items:center;gap:12px;flex-wrap:wrap;min-width:0}
.card-header-title{margin:0}

.source-badge{
  display:inline-block;
  padding:10px 14px;
  border-radius:999px;
  background:var(--accent-soft);
  color:#0a67b8;
  font-size:16px;
  font-weight:700;
}

.card-status{
  font-size:14px;
  font-weight:700;
  padding:9px 14px;
  border-radius:999px;
  white-space:nowrap;
  line-height:1.4;
}
.card-status-loading{background:#f1f5f9;color:#6b7280;border:1px solid #e2e8f0}
.card-status-ok{background:var(--success-bg);color:var(--success-text);border:1px solid var(--success-border)}
.card-status-empty{background:#f1f5f9;color:#9ca3af;border:1px solid #e2e8f0}
.card-status-error{background:var(--danger-bg);color:var(--danger-text);border:1px solid var(--danger-border)}

.card-toggle-icon{
  width:34px;
  height:34px;
  border-radius:50%;
  display:inline-flex;
  align-items:center;
  justify-content:center;
  background:#f2f6fb;
  color:#94a3b8;
  font-size:12px;
  transform:rotate(-90deg);
  transition:transform .2s;
  flex-shrink:0;
}

.card:not(.collapsed) .card-toggle-icon{transform:rotate(0deg)}
.card.collapsed .card-content{display:none}
.card-content{padding:18px 22px 22px}

.result-grid{display:grid;grid-template-columns:1fr 320px;gap:12px}
.result-left{min-height:80px}
.result-right{background:#fbfdff;padding:10px;border-radius:8px}

.hint{color:var(--muted)}

.footer{
  max-width:1600px;
  margin:18px auto 14px;
  padding:0 28px;
  font-size:16px;
  color:#607089;
}

.chat-toggle-btn{
  margin-left:auto;
  background:#2c4066;
  border:none;
  color:#fff;
  padding:8px 14px;
  border-radius:8px;
  cursor:pointer;
  font-size:13px;
  font-weight:600;
  display:flex;
  align-items:center;
  gap:7px;
  transition:background .15s;
  white-space:nowrap;
}
.chat-toggle-btn:hover{background:#1fa97a}

.chat-overlay{
  display:none;
  position:fixed;
  inset:0;
  background:rgba(0,0,0,0.35);
  z-index:1000;
}
.chat-overlay.open{display:block}

.chat-panel{
  position:fixed;
  right:0;
  top:0;
  bottom:0;
  width:420px;
  max-width:100vw;
  background:#fff;
  box-shadow:-4px 0 32px rgba(7,43,79,0.14);
  z-index:1001;
  display:flex;
  flex-direction:column;
  transform:translateX(100%);
  transition:transform .25s cubic-bezier(.4,0,.2,1);
  font-size:14px;
}
.chat-panel.open{transform:translateX(0)}

.chat-panel-header{
  background:linear-gradient(90deg,#072b4f 0%,#0b6fbf 100%);
  color:#fff;
  padding:14px 16px;
  display:flex;
  align-items:center;
  justify-content:space-between;
  flex-shrink:0;
}
.chat-panel-title{display:flex;align-items:center;gap:8px;font-weight:700;font-size:15px}
.chat-badge{
  background:rgba(255,255,255,0.22);
  border:1px solid rgba(255,255,255,0.4);
  border-radius:4px;
  font-size:10px;
  font-weight:700;
  padding:1px 5px;
  letter-spacing:.04em;
}
.chat-panel-actions{display:flex;gap:6px}
.chat-action-btn{
  background:rgba(255,255,255,0.12);
  border:1px solid rgba(255,255,255,0.25);
  color:#fff;
  border-radius:6px;
  padding:4px 7px;
  cursor:pointer;
  display:flex;
  align-items:center;
}

.chat-messages{
  flex:1;
  overflow-y:auto;
  padding:16px;
  display:flex;
  flex-direction:column;
  gap:14px;
}
.chat-message{display:flex;gap:10px;align-items:flex-start}
.chat-avatar{
  width:30px;
  height:30px;
  border-radius:50%;
  background:linear-gradient(135deg,#0b6fbf,#072b4f);
  color:#fff;
  font-weight:700;
  font-size:13px;
  display:flex;
  align-items:center;
  justify-content:center;
  flex-shrink:0;
}
.chat-message.user .chat-avatar{background:linear-gradient(135deg,#10b981,#059669)}
.chat-bubble{
  background:#f1f5f9;
  padding:10px 13px;
  border-radius:2px 12px 12px 12px;
  max-width:86%;
  line-height:1.55;
  word-break:break-word;
}
.chat-message.user .chat-bubble{
  background:#eef6ff;
  border-left:3px solid #0b6fbf;
}
.chat-bubble p{margin:0 0 7px 0}
.chat-bubble p:last-child{margin-bottom:0}
.chat-bubble code{background:#e8f0fb;padding:1px 5px;border-radius:4px;font-size:12px}
.chat-bubble pre{background:#1e293b;color:#e2e8f0;padding:10px;border-radius:8px;overflow-x:auto;font-size:12px;margin:6px 0}
.chat-bubble pre code{background:none;color:inherit;padding:0}
.chat-bubble table{border-collapse:collapse;width:100%;font-size:12px;margin:6px 0}
.chat-bubble th,.chat-bubble td{border:1px solid #cbd5e1;padding:5px 8px;text-align:left}
.chat-bubble th{background:#f1f5f9;font-weight:600}
.chat-bubble a{color:#0b6fbf}
.chat-bubble h3,.chat-bubble h4{margin:10px 0 4px 0;font-size:13px}
.chat-bubble hr{border:none;border-top:1px solid #e2e8f0;margin:8px 0}
.chat-bubble ul,.chat-bubble ol{margin:4px 0;padding-left:18px}

.chat-suggestions{display:flex;flex-wrap:wrap;gap:6px;padding:10px 12px 4px}
.chat-suggestion{
  background:#eef6ff;
  border:1px solid #c3daf7;
  color:#0b6fbf;
  border-radius:20px;
  padding:4px 11px;
  font-size:12px;
  cursor:pointer;
}

.chat-input-area{
  border-top:1px solid #e9eef5;
  padding:10px 12px 12px;
  flex-shrink:0;
  background:#fff;
}
.chat-input-row{display:flex;gap:8px;align-items:flex-end}
.chat-input-row textarea{
  flex:1;
  border:1px solid #dce6f0;
  border-radius:10px;
  padding:9px 12px;
  font-size:13px;
  font-family:inherit;
  resize:none;
  line-height:1.5;
  outline:none;
  max-height:140px;
  overflow-y:auto;
}
.chat-input-row textarea:focus{border-color:#0b6fbf}
#chatSendBtn{
  background:var(--accent);
  border:none;
  color:#fff;
  border-radius:10px;
  padding:9px 13px;
  cursor:pointer;
  display:flex;
  align-items:center;
  flex-shrink:0;
}
#chatSendBtn:disabled{background:#9ec3e8;cursor:not-allowed}
.chat-footer-note{font-size:11px;color:#9ca3af;text-align:center;margin-top:7px}

.fp-card{background:#fff;border-radius:14px;box-shadow:0 6px 28px rgba(7,43,79,0.08);overflow:hidden;margin-bottom:18px}
.fp-header{background:linear-gradient(100deg,#072b4f 0%,#0d5faa 60%,#1480d4 100%);padding:18px 22px;color:#fff}
.fp-title-row{display:flex;align-items:center;flex-wrap:wrap;gap:8px;margin-bottom:6px}
.fp-title{font-size:17px;font-weight:700;line-height:1.3;flex:1;min-width:0;word-break:break-word}
.fp-cas-badge,.fp-formula-badge{background:rgba(255,255,255,0.2);border:1px solid rgba(255,255,255,0.35);border-radius:6px;padding:3px 9px;font-size:12px;font-weight:600;white-space:nowrap}
.fp-formula-badge{font-family:monospace}
.fp-wiki-strip{margin-top:8px;font-size:12.5px;opacity:0.9;line-height:1.5}
.fp-wiki-strip a{color:#7dd3fc}
.fp-section{border-bottom:1px solid #eef2f7;padding:14px 22px}
.fp-section:last-child{border-bottom:none}
.fp-section-title{font-size:12px;font-weight:700;text-transform:uppercase;letter-spacing:.06em;color:#0b6fbf;margin-bottom:10px;display:flex;align-items:center;gap:5px}
.fp-table{width:100%;border-collapse:collapse;font-size:13px}
.fp-td-label{padding:5px 10px 5px 0;width:170px;color:#6b7280;vertical-align:top;white-space:nowrap}
.fp-td-val{padding:5px 0;color:#111;word-break:break-word}
.fp-td-mono{font-size:11.5px}
.fp-code{background:#e8f0fb;padding:1px 6px;border-radius:4px;font-size:11.5px;font-family:monospace;word-break:break-all}
.fp-code-wrap{background:#f1f5f9;padding:2px 6px;border-radius:4px;font-size:11.5px;font-family:monospace;display:inline-block;max-width:100%;word-break:break-all;white-space:pre-wrap}
.fp-lipinski{font-size:12px;padding:6px 10px;border-radius:7px;margin-bottom:10px;display:inline-block}
.fp-lip-pass{background:#d1fae5;color:#065f46;border:1px solid #6ee7b7}
.fp-lip-fail{background:#fef3c7;color:#92400e;border:1px solid #fbbf24}
.fp-db-grid,.fp-supplier-grid{display:grid;grid-template-columns:repeat(auto-fill,minmax(160px,1fr));gap:8px}
.fp-supplier-grid{grid-template-columns:repeat(auto-fill,minmax(170px,1fr));gap:7px}
.fp-db-card,.fp-supplier-card{
  display:flex;align-items:center;gap:7px;padding:8px 11px;border:1px solid #e2e8f0;border-radius:8px;
  text-decoration:none;background:#fafcff;transition:border-color .15s,background .15s;
}
.fp-db-card{color:#111;font-size:12.5px;font-weight:500}
.fp-supplier-card{justify-content:space-between;color:#0b6fbf;font-size:12.5px;font-weight:500;background:#f8fafd}
.fp-db-card:hover,.fp-supplier-card:hover{border-color:#0b6fbf;background:#eef6ff}
.fp-db-name{flex:1;min-width:0;overflow:hidden;text-overflow:ellipsis;white-space:nowrap}
.fp-synonyms{display:flex;flex-wrap:wrap;gap:5px}
.fp-syn-tag{background:#f1f5f9;border:1px solid #e2e8f0;border-radius:20px;padding:3px 10px;font-size:11.5px;color:#374151}
.fp-notfound{padding:14px;color:#6b7280;font-size:14px}
.fp-spinner{width:20px;height:20px;border:2px solid #d1e7f7;border-top-color:#0b6fbf;border-radius:50%;animation:fp-spin .7s linear infinite;flex-shrink:0}
@keyframes fp-spin{to{transform:rotate(360deg)}}
.fp-loading{padding:16px 18px}

.bdb-card{background:#fff;border:1px solid #eef2f7;border-radius:8px;padding:10px 12px;margin-bottom:8px}
.bdb-card-header{display:flex;align-items:flex-start;justify-content:space-between;gap:8px;flex-wrap:wrap;margin-bottom:4px}
.bdb-card-header strong{font-size:13.5px;color:#111;flex:1;min-width:0}
.bdb-badges{display:flex;flex-wrap:wrap;gap:4px;flex-shrink:0}
.bdb-badge{font-size:10.5px;font-weight:700;padding:2px 7px;border-radius:12px;white-space:nowrap}
.bdb-ki{background:#dbeafe;color:#1e40af}
.bdb-kd{background:#d1fae5;color:#065f46}
.bdb-ic50{background:#fef3c7;color:#92400e}
.bdb-ec50{background:#ede9fe;color:#5b21b6}
.bdb-target{font-size:12px;color:#374151;margin:4px 0 2px}
.bdb-organism{color:#6b7280;font-size:11px}
.bdb-props{display:flex;flex-wrap:wrap;gap:4px;margin:5px 0}
.bdb-prop{font-size:11px;background:#f1f5f9;border:1px solid #e2e8f0;border-radius:4px;padding:1px 6px;color:#374151}
.bdb-smiles{font-size:11px;color:#6b7280;margin:4px 0;word-break:break-all}
.bdb-smiles code{background:#f8fafc;padding:2px 5px;border-radius:3px}
.bdb-links{margin-top:6px;font-size:11px;display:flex;flex-wrap:wrap;gap:8px}

.src-picker{position:relative}
.src-picker-btn{
  display:inline-flex;
  align-items:center;
  gap:6px;
  min-height:46px;
  padding:0 16px;
  background:rgba(255,255,255,0.92);
  border:1px solid #d1dce8;
  border-radius:14px;
  font-size:15px;
  font-weight:700;
  color:#334155;
  cursor:pointer;
  user-select:none;
  transition:border-color .15s,box-shadow .15s;
  white-space:nowrap;
}
.src-picker-btn:hover,
.src-picker-btn.open{
  border-color:#0b6fbf;
  box-shadow:0 0 0 3px #0b6fbf18;
}
.src-picker-caret{transition:transform .2s;opacity:.6}
.src-picker-btn.open .src-picker-caret{transform:rotate(180deg)}

.src-picker-dropdown{
  position:absolute;
  top:calc(100% + 10px);
  left:0;
  min-width:370px;
  max-width:min(92vw, 430px);
  background:#fff;
  border:1px solid #d8e1eb;
  border-radius:16px;
  box-shadow:0 20px 48px rgba(15,23,42,0.16);
  display:none;
  z-index:80;
  overflow:hidden;
}
.src-picker-dropdown.open{display:block}
.src-picker-header{
  padding:14px 16px 10px;
  font-size:12px;
  font-weight:700;
  text-transform:uppercase;
  letter-spacing:.06em;
  color:#64748b;
  background:#f8fbff;
}
.src-picker-hint{font-size:10px;font-weight:400;text-transform:none;letter-spacing:0;color:#9ca3af}
.src-picker-list{list-style:none;margin:0;padding:6px 0;max-height:380px;overflow:auto}
.src-picker-item{
  display:grid;
  grid-template-columns:18px auto 1fr;
  gap:10px;
  align-items:center;
  padding:10px 16px;
  cursor:pointer;
}
.src-picker-item:hover{background:#f8faff}
.src-picker-item.selected{background:#f0f7ff}
.src-picker-item.selected:hover{background:#e7f2ff}
.src-item-check{
  width:18px;
  color:#0b6fbf;
  font-size:13px;
  font-weight:700;
}
.src-item-badge{
  display:inline-flex;
  align-items:center;
  padding:5px 9px;
  border-radius:999px;
  font-size:12px;
  font-weight:700;
  white-space:nowrap;
}
.src-item-desc{font-size:12px;color:#64748b;min-width:0}
.src-badge-pubchem{background:#e0f2fe;color:#0369a1}
.src-badge-chembl{background:#ecfdf5;color:#065f46}
.src-badge-europepmc{background:#fef3c7;color:#92400e}
.src-badge-bindingdb{background:#ede9fe;color:#5b21b6}
.src-badge-rcsb{background:#dbeafe;color:#1d4ed8}
.src-badge-drugbank{background:#fff7ed;color:#9a3412}
.src-badge-toxnet{background:#fee2e2;color:#b91c1c}
.src-badge-tox21{background:#dcfce7;color:#166534}
.src-badge-chemrxiv{background:#fae8ff;color:#a21caf}
.src-badge-semanticscholar{background:#e0e7ff;color:#3730a3}
.src-badge-materialsproject{background:#ecfeff;color:#0f766e}
.src-badge-aflow{background:#f1f5f9;color:#334155}
.src-picker-footer{
  display:flex;
  gap:8px;
  justify-content:flex-end;
  padding:12px 16px 14px;
  border-top:1px solid #edf2f7;
  background:#fbfdff;
}
.src-picker-all{
  border:1px solid #d7e2ee;
  background:#fff;
  color:#334155;
  border-radius:10px;
  padding:7px 12px;
  font-size:12px;
  font-weight:700;
  cursor:pointer;
}
.src-picker-all:hover{background:#eef6ff}

@media (max-width:1180px){
  .search-controls{grid-template-columns:minmax(0,1fr) auto}
  #searchBtn{grid-column:2}
}

@media (max-width:860px){
  .container{padding:0 16px}
  .search-panel{padding:18px;border-radius:18px}
  .search-controls{grid-template-columns:1fr}
  .search-controls input{
    min-height:58px;
    padding:16px 118px 16px 16px;
    font-size:16px;
  }
  #fullProfileBtn,
  #searchBtn{
    width:100%;
    min-height:54px;
  }
  .source-badge{font-size:15px}
  .card-status{font-size:13px}
  .card-header{padding:16px}
  .result-grid{grid-template-columns:1fr}
  .footer{padding:0 16px;font-size:14px}
  .src-picker-dropdown{min-width:min(92vw,370px)}
}

@media (max-width:600px){
  .topbar{
    height:auto;
    padding:12px 16px;
    flex-wrap:wrap;
  }
  .topbar .subtitle{width:100%;order:3}
}

@media (max-width:480px){
  .chat-panel{width:100vw}
}