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156154 37 9 | Cheminformatics

Chemical : Hydrochlorothiazide mixture with Losartan

Casrn : 156154-37-9

MolName : Hydrochlorothiazide mixture with Losartan

MolecularFormula : K.C7H8N3O4ClS2.C22H22N6OCl

Smiles : CCCCc1nc(Cl)c(CO)n1Cc(cc1)ccc1-c(cccc1)c1-c1nnn[n-]1.NS(c(cc(c(NCN1)c2)S1(=O)=O)c2Cl)(=O)=O.[K+]

InChI : InChI=1S/C22H22ClN6O.C7H8ClN3O4S2.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;1-2,10-11H,3H2,(H2,9,12,13);/q-1;;+1

InChIK : XRKMYXDEMOEFBN-UHFFFAOYSA-N

CanonicalSyTyLFy : 553af8c78c0ccfec

TotalMolweight : 758.751

Molweight : 421.911

MonoisotopicMass : 421.154361

CLogP : 4.0501

CLogS : -4.986

H Acceptors : 7

H Donors : 1

TotalSurfaceArea : 315.19

Relative PSA : 0.20258

PolarSurfaceArea : 76.72

Druglikeness : -3.665

Mutagenic : none

Tumorigenic : none

Reproductive Effective : none

Irritant : none

Nasty Functions :

Shape Index : 0.53333

Molecula Flexibility : 0.50279

Molecular Complexity : 0.86255

Fragments : 3

Non HAtoms : 30

NonCHAtoms : 8

Electronegative Atoms : 8

Rotatable Bond : 8

Rings Closures : 4

Small Rings : 4

Aromatic Rings : 4

Aromatic Atoms : 22

Sp3Atoms : 7

Symmetricatoms : 2

Aromatic Nitrogens : 6

BasicNitrogens : 1

StereoCon :

CAS Number Mutagenic Tumorigenic Irritant Molecule Formula Mol Weight Druglikeness
100004-95-3nonenonenoneC13H11NO3229.234-1.3547
1000339-36-5nonenonenoneC16H19NO3S305.397-3.4866
1000068-23-4nonelownoneC14H18NO5B291.11-44.603
1000018-40-5lowhighnoneC11H16N2O2S240.3261.4856
100-74-3highnonehighC6H13NO115.1753.7593
1000339-23-0nonenonenoneC6H5N2O2Br217.022-3.3311
1000339-27-4nonenonenoneC14H8N3O3Br346.14-5.8142
100004-94-2nonenonenoneC13H11NO2213.235-1.5864
100-21-0highnonehighC8H6O4166.132-1.8442
10003-73-3nonenonenoneHCl.C7H10N2122.17-2.0712
100019-40-7nonenonenoneC14H15NO3245.277-1.947
100008-89-7nonenonenoneC11H10N4O3246.225-1.8465
100-58-3nonenonenoneBr.C6H5Mg101.411-2.3575
1000025-93-3nonenonenoneC20H17NO4335.358-1.6731
10001-08-8nonenonehighC11H22N2O198.309-3.1037
100007-62-3nonenonehighC8H13NO139.197-8.1398
1000269-68-0nonenonenoneC14H24N4248.3730.99367
10-35-5nonenonenoneC4H6O2BrF184.992-23.473
1000-00-6nonenonehighC10H26OSi2218.487-62.76
1000018-13-2nonenonenoneC11H14NO2Br272.141-5.4951
1000018-59-6nonenonelowC10H15O2BrS279.197-14.078
1000160-75-7nonenonelowC14H17O2BS260.164-20.35
100021-79-2nonehighhighC16H32O2.C2H8N2256.428-25.216
100010-00-2nonenonenoneC20H23NO5357.405-3.7157
1000-67-5nonenonehighC4H9O4S.Na153.177-10.412
100016-58-8nonehighnoneC19H19NO5341.3621.8385
100-07-2highhighlowC8H7O2Cl170.595-10.49
100-17-4nonenonenoneC7H7NO3153.137-7.2945
100-18-5nonenonenoneC12H18162.275-2.5088
100-68-5nonenonenoneC7H8S124.207-1.735
100-93-6highhighhighC19H18N2O2S338.43-12.848
1000-70-0nonelowhighC7H18N2Si2186.406-43.673
100-32-3nonenonenoneC12H8N2O4S2308.338-7.3436
1000018-07-4nonenonenoneC14H13N3O239.2771.9531
100-33-4nonenonenoneC19H24N4O2340.426-7.2784
10003-95-9nonenonenoneC10H18N2O17P4562.146-25.989
100-79-8nonelownoneC6H12O3132.158-9.8672
1000-90-4nonenonenoneZn.C4H7OS2.C4H7OS2135.231-2.7683
1000018-51-8nonenonenoneC10H10N2O2S2254.3331.3137
017257-81-7nonenonenoneC6H10O2114.1430.9106
100027-90-5highhighnoneC20H26N2Cl2.HCl.HCl365.3464.1664
100-39-0highhighnoneC7H7Br171.037-7.8241
1000017-93-5nonenonenoneC8H5N2O2Cl196.5932.9136
100-64-1highhighnoneC6H11NO113.159-6.4182
1000284-35-4nonenonehighC16H24O4280.363-11.936
10-18-2004nonenonenoneC6H8OS2160.261-3.1913
10002-37-6nonenonenoneC9H16N2O168.239-3.8085
100-41-4highhighhighC8H10106.167-2.68
100031-92-3nonenonehighC10H30OSi4278.691-53.619
100-62-9lownonenoneC7H7N105.14-1.1924
100021-82-7nonenonenoneH3O4P.C18H38N2O298.513-22.282
100004-80-6nonenonenoneC13H11NO3229.234-1.3547
1000339-26-3nonenonenoneC14H7N2OBrCl2370.033-0.59356
100-85-6nonenonenoneHO.C10H16N150.244-2.6575
100008-84-2nonenonenoneC22H14N2O2338.3653.1859
10001-51-1nonenonenoneC9H18N2O170.2555.9677
1000339-54-7nonenonenoneC9H7O2F3204.147-11.176
100004-54-4nonehighnoneC4H8Te183.708-3.9699
10000-20-1nonelowhighC12H32N2Si2260.572-64.51
1000339-24-1nonenonenoneC7H4NOF137.113-7.3916