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316371 84 3 | Cheminformatics

Chemical : Rosiglitazone (potassium salt)

Casrn : 316371-84-3

MolName : Rosiglitazone (potassium salt)

MolecularFormula : K.C18H18N3O3S

Smiles : CN(CCOc1ccc(CC(C([N-]2)=O)SC2=O)cc1)c1ncccc1.[K+]

InChI : InChI=1S/C18H19N3O3S.K/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15;/h2-9,15H,10-12H2,1H3,(H,20,22,23);/q;+1/p-1/t15-;/m0./s1

InChIK : RWOGCLSZSSKLEN-RSAXXLAASA-M

CanonicalSyTyLFy : 574243ca0975d27d

TotalMolweight : 395.523

Molweight : 356.425

MonoisotopicMass : 356.106887

CLogP : 1.9008

CLogS : -3.666

H Acceptors : 6

TotalSurfaceArea : 257.61

Relative PSA : 0.26431

PolarSurfaceArea : 84.8

Druglikeness : 5.9692

Mutagenic : none

Tumorigenic : none

Reproductive Effective : none

Irritant : none

Nasty Functions :

Shape Index : 0.68

Molecula Flexibility : 0.53192

Molecular Complexity : 0.70181

Fragments : 2

Non HAtoms : 25

NonCHAtoms : 7

Electronegative Atoms : 7

StereoCenters : 1

Rotatable Bond : 7

Rings Closures : 3

Small Rings : 3

Aromatic Rings : 2

Aromatic Atoms : 12

Sp3Atoms : 7

Symmetricatoms : 2

Amides : 1

Aromatic Nitrogens : 1

BasicNitrogens : 1

StereoCon : racemate

CAS Number Mutagenic Tumorigenic Irritant Molecule Formula Mol Weight Druglikeness
10002-97-8nonenonenoneC18H30O2278.4340.24997
100016-58-8nonehighnoneC19H19NO5341.3621.8385
100-87-8nonenonenoneC7H8O3S172.204-10.732
1000017-93-5nonenonenoneC8H5N2O2Cl196.5932.9136
1000025-93-3nonenonenoneC20H17NO4335.358-1.6731
100012-67-7highhighhighC12H12O5236.222-19.846
100-62-9lownonenoneC7H7N105.14-1.1924
1000018-25-6nonenonenoneC13H24N2O6S336.408-32.405
100-19-6nonenonenoneC8H7NO3165.148-7.0365
1000068-65-4nonenonenoneC13H15NO4BF279.074-46.077
100-45-8nonenonehighC7H9N107.155-10.018
1000339-32-1nonenonenoneC11H14NF179.2370.6275
1000018-39-2highhighlowC13H20N2O2S268.381.9315
100-46-9nonenonenoneC7H9N107.155-2.0712
100-44-7highhighnoneC7H7Cl126.586-2.365
100018-96-0highhighnoneC20H39O2I438.428-31.232
1000339-26-3nonenonenoneC14H7N2OBrCl2370.033-0.59356
1000018-49-4nonenonenoneC14H19NO5S313.3732.5797
1000-77-7highhighnoneHCl.C6H15NO6S2261.3181.5333
100-54-9nonenonenoneC6H4N2104.112-6.0498
10003-42-6nonenonenoneC11H11NO4221.211-4.7046
10001-08-8nonenonehighC11H22N2O198.309-3.1037
100-15-2nonehighnoneC7H8N2O2152.153-5.7806
1000269-51-1nonenonenoneC13H12NO4B257.052-12.285
100-67-4nonenonenoneK.C6H5O93.1047-2.2548
100-95-8nonenonenoneCl.C23H41N2O361.592-17.647
100005-68-3nonenonenoneC13H12O4232.234-4.9451
10003-67-5nonenonenoneC33H62O6554.849-22.973
1000296-71-8nonenonehighC19H27NO8S3493.62-2.9952
100005-44-5highnonelowC7H5O2ClS188.634-11.771
100-64-1highhighnoneC6H11NO113.159-6.4182
1000068-24-5nonenonelowC13H15NO4BCl295.529-44.638
1000269-66-8nonenonenoneC12H20N4220.3190.5423
100031-88-7nonenonehighC10H30O3Si4310.689-53.619
100004-54-4nonehighnoneC4H8Te183.708-3.9699
100011-01-6nonenonenoneC9H18O2158.24-2.3462
100004-79-3nonenonenoneC13H11NO2213.235-1.5864
1000296-70-7nonenonenoneC19H27NO7S3477.6213.1322
1000010-11-6nonenonenoneC28H44N2O2440.669-21.689
100010-00-2nonenonenoneC20H23NO5357.405-3.7157
1000-83-5lowhighhighC2H6N2OS106.149-2.264
100-47-0highnonehighC7H5N103.124-6.0498
1000017-97-9nonenonenoneC10H11N3O2205.216-1.3937
1000-22-2lowhighlowC6H14O2FPS200.213-11.052
1000284-53-6nonenonehighC18H36O2284.482-15.583
1000198-76-4nonenonenoneC11H12NF3215.217-5.8988
1000339-27-4nonenonenoneC14H8N3O3Br346.14-5.8142
1000171-05-0nonenonenoneC27H37O3P440.562-24.592
1000-46-0nonenonenoneC7H18Ge174.83-4.6976
100007-55-4nonenonenoneC35H39O19763.676-1.2907
100-70-9nonenonenoneC6H4N2104.112-6.0498
100033-28-1lownonehighC6H9N7179.186-2.3035
100-77-6nonenonenoneC6H4N2Cl.Cl139.565-4.1248
100005-79-6nonenonenoneC12H9NS199.276-2.6106
100-89-0nonenonelowC18H36O6B2370.1-16.157
100020-94-8highnonelowC12H17OCl212.719-11.962
10003-95-9nonenonenoneC10H18N2O17P4562.146-25.989
100007-40-7nonenonenoneC31H42N4O7582.695-0.42167
100004-95-3nonenonenoneC13H11NO3229.234-1.3547
100002-29-7nonenonenoneC12H18N2O3238.2862.8956